B (de la Pradilla), Sanguiin H-5 (Spring), Solandelactone A (White), Spirastrellolide A (Paterson) Richard J. K. Taylor of the University of York has developed (Angew. Buy2422999-74-2 Chem. Int. Ed. PMID:23892407…
(-)-Ushikolide A (4), isolated from a culture broth of Streptomyces sp. IUK-102, showed powerful activity against murine splenic lymphocyte proliferation (IC50 = 70 nM). The most important player in the…
The total synthesis of Epothilone B (4), the first natural product (with Epothilone A) to show the same microtubule-stabilizing activity as paclitaxel (Taxol®), has attracted a great deal of attention…
There are currently 61 known vibsane-type diterpenes, as exemplified by (-)-5-epi-Vibsanin E (3). The first synthesis of 3, described (J. Price of 79208-84-7 Am. Chem. Soc. 2009, 131, 8329. DOI:…
Conjugate addition-enolate trapping, a strategy originally developed by Gilbert Stork, has become a powerful method for stereocontrolled ring construction. A key step in the synthesis of (-)-Clavirolide C (3) reported…
The enantioselective addition of allyl organometallics to carbonyls has become one of the workhorses of organic synthesis. PMID:24318587 Dennis Hall of the University of Alberta reports (J. Am. Chem. Soc.…
Cells to insoluble purple formazan dye crystals. One hundred microliters per nicely of dimethyl sulfoxide (DMSO) was employed for the soluble crystals, along with the absorbance was study using a…
Were morphometrically analyzed by measuring the total emptied location standardized over the total tissue location. Briefly, the outer border in the spinal cord section was identified to delineate the website…
High yielding ultrasound mediated three-component synthesis of substituted propargylamines Sreedhar and co-workers from Indian Institute of Chemical Technology have described a mild one-pot, three-component synthesis of substituted propargylamines by using…
Welwitindolinone A Isonitrile (3) is the first of a family of oxindole natural products isolated from the cyanobacteria Hapalosiphon welwischii and Westiella intricate on the basis of their activity for…
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