Ng oestrogen and progesterone receptors and HER-2 gene amplification, account for ten?0 of all breast carcinomas in Asian and Western populations (Thike et al, 2010; De Ruijter et al, 2011).…
For synthesis of higher polyamines, putrescine controls the self-processing conversion of SAM decarboxylase (AMD1) proenzyme for the active enzyme (Pegg, 2009). Moreover, putrescine can bind an allosteric site in AMD1…
Vinyl glycine 2 is a useful precursor to a variety of amino acids. PMID:23789847 Timothy E. Long of the University of Georgia found (Tetrahedron Lett. 2009, 50, 5067. DOI: 10.1016/j.tetlet.2009.06.082)…
(+)-Rotundial Karl Anker Jørgensen of Aarhus University found (Angew. Chem. Int. 1075198-30-9 Formula Ed. 2009, 48, 6650. DOI: 10.1002/ange.200903253) that an organocatalyst could mediate the fragmentation of the prochiral cyclopropane…
Masato Kitamura of Nagoya University investigated (Chem. Lett. 2009, 38, 188. DOI: 10.1246/cl.2009.188) the Ru-mediated deprotection of allyl ethers such as 1. The same catalyst was effective for the preparation…
Keiji Maruoka of Kyoto University found (Org. 8-Bromoquinazoline-2,4-diol Purity Lett. 2010, 12, 1668. DOI: 10.1021/ol100104v) that the diazo amide 1 derived from the Oppolzer sultam condensed with the imine 2…
Varinder K. Aggarwal of the University of Bristol showed(Angew. Chem. Int. Ed. 2009, 48, 1149.DOI: 10.1002/anie.200805272)that condensation of a boronic ester 2 with a metalatedaziridine 1 led, after oxidation, to…
Enantioselective target-directed synthesis, which is important both for single-enantiomer pharmaceuticals and for natural product total synthesis, depends on the ability to form carbon-carbon bonds with absolute stereocontrol. Ethyl 4-methyl-1H-pyrrole-2-carboxylate Formula…
Yuqing Hou of Southern Illinois University found (J. Org. Chem. PMID:24187611 2009, 74, 6362. DOI: 10.1021/jo901086s) that the peroxy ether 2 served effectively to directly transfer a methoxy group to…
E (FITC), anti B7-H1 mAb (eBioscience, Minneapolis, MN), and anti-mouse immunoglobulin conjugated with FITC (Dako Denmark A/S, Glostrup, Denmark). Detection of surface CD80 and CD86 was carried out employing unconjugated…
Chemexpress