Product Name :
NKX3.1 Recombinant Rabbit Monoclonal Antibody [JE36-27]
Predicted band size :
26 kDa
Observed band size :
30 kDa
Synonyms:
BAPX 2 antibody BAPX2 antibody Homeobox protein NK-3 homolog A antibody Homeobox protein Nkx 3.1 antibody Homeobox protein Nkx-3.1 antibody Homeobox protein Nkx3.1 antibody NK homeobox (Drosophila) family 3 A antibody NK homeobox family 3 A antibody NK homeobox, family 3, member A antibody NK3 homeobox 1 antibody 展开
Function :
Homeobox protein Nkx-3.1, also known as NKX3-1, NKX3, BAPX2, NKX3A and NKX3.1 is a protein that in humans is encoded by the NKX3-1 gene located on chromosome 8p. NKX3-1 is a prostatic tumor suppressor gene. NKX3-1 is an androgen-regulated, prostate-specific homeobox gene whose expression is predominantly localized to prostate epithelium. It acts as a transcription factor that has critical function in prostate development and tumor suppression. It is a negative regulator of epithelial cell growth in prostate tissue. The NKX3-1 homeobox protein is encoded by the NKX3-1 gene. The homeodomain-containing transcription factor NKX3A is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3A protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within Human NKX3.1 aa 1-234 / 234.
Species reactivity:
Human
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
JE36-27
RRID:
AB_3072500
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃.2,2-Bis(bromomethyl)-1,3-dioxolane structure Avoid repeated freeze / thaw cycles.Hex-5-yn-1-ol Chemscene
Storage buffer solution:
1*TBS (pH7.PMID:33687113 4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 26 kDa
Positive control :
A549 cell lysate, RWPE-1 cell lysate, human prostate tissue, human prostate carcinoma tissue, human testis tissue.