N6 PUFAs in phospholipids (data not shown). Pearson correlation coefficient was calculated to assess correlation involving every PUFA. In phospholipids,Kume et al. Nutrition Metabolism 2013, 10:41 http://www.nutritionandmetabolism.com/content/10/1/Page 4 ofTable 1 Characteristics of the subjects according to tertile of n3 PUFA and n6 PUFA in serum cholesterol estern3 PUFA T1 (two.74)1 No. of subjects Age (y, imply SD) Sex (male, ) Workplace (A, )n6 PUFA T3 (five.79) 165 47.7 9.8 68.5 29.7 23.0 three.2 32.7 58.2 83.six 30.three 0.001 0.001 0.75 0.01 0.02 0.001 0.12 0.60 0.002 Ptrend2 T1 (58.36) 166 47.9 10.1 79.five 29.5 23.five three.5 43.four 64.5 81.9 36.8 T2 (62.58) 165 41.4 ten.four 57.0 31.five 22.3 three.five 26.1 35.2 84.two 30.3 T3 (66.18) Ptrend 165 38.1 8.9 38.8 31.five 21.6 3.two 12.7 27.3 75.2 20.6 0.001 0.001 0.69 0.001 0.001 0.001 0.42 0.001 0.T2 (4.01) 165 41.eight ten.5 54.six 31.five 22.5 three.9 28.five 40.0 77.six 29.166 37.9 9.3 52.four 31.three 21.9 three.3 21.1 28.9 80.1 27.Physique Mass Index (kg/m2, imply SD) Current smoking ( ) Alcohol consumption (20 g of ethanol/d, ) Occupational physical activity (sedentary, ) Nonoccupational physical activity (five METh/wk, ) Serum folate (ng/ml) Dietary intake of vitamin B6 (mg/1000 kcal, imply SD) Dietary intake of vitamin B12 (g/1000 kcal)3.1403257-80-6 Chemscene four (2.BuyFmoc-L-Lys (Boc)-OH 6, four.9)four three.eight (2.7, 5.0) 4.3 (three.1, five.8)three.4 (2.7, four.7) 3.8 (two.7, five.7) four.0 (3.0, five.3)0.6 0.2 3.9 (2.8, 5.0)0.7 0.0.7 0.0.0.6 0.0.7 0.0.7 0.0.PMID:23357584 four.1 (3.1, five.2) five.1 (four.0, six.two) 0.4.eight (three.6, 6.1) four.three (3.0, five.9) four.0 (three.0, 5.0) 0.Abbreviations: T Tertile, PUFA Polyunsaturated fatty acids, SD Standard deviation, MET Metabolic equivalent. 1 Median percentage of n3 PUFA or n6 PUFA (all such values). two Ptrend values have been based on the MantelHaenszel chisquare test for categorical variables and on linear regression analysis for continuous variables,with ordinal numbers 0 assigned to tertile categories of each and every fatty acid. 3 A, workplace surveyed in July. 4 Median (interquartile range) of serum folate and dietary intake of vitamin B12.relatively strong correlations (absolute value of r 0.6) had been observed amongst DHA and DPA (r = 0.71), amongst LA and EPA (r = 0.60), and between LA and DHA (r = 0.60). As regards CE, comparatively sturdy correlations (absolute value of r 0.six) had been observed among EPA and DHA (r = 0.70), between GLA and DGLA (r = 0.64). The correlation coefficients of total PUFA with n6 PUFA and n3 PUFA in phospholipids have been 0.42 and 0.35, respectively, whereas the corresponding figures in CE have been 0.91 and 0.07, respectively. Serum homocysteine concentration showed comparatively sturdy, inverse correlation with serum folate (r = 0.53) and moderate, inverse correlation with dietary intake of folate (r = 0.30) and vitamin B6 (r = 0.28), but not with dietary vitamin B12 (r = 0.05). The relation among serum phospholipids fatty acid composition and homocysteine concentration is shown in Table 2. Homocysteine concentration was significantly reduce with growing levels of total n3 PUFA, EPA and DHA in age, sex and workplaceadjusted model (Ptrend = 0.02, 0.01 and 0.003, respectively). In the fully adjusted model, the associations or total n3 PUFA and EPA were attenuated (Ptrend = 0.36 and 0.12, respectively), whereas that for DHA remained statistically important (Ptrend = 0.04). Total n6 PUFA and its elements weren’t drastically linked with homocysteine concentration in either model. The relation among serum CE fatty acid composition and homocysteine concentration is shown in Table three.A considerable inverse association wa.