Product Name :
Nuf2 Recombinant Rabbit Monoclonal Antibody [JG34-64]
Predicted band size :
Observed band size :
Synonyms:
Cancer/testis antigen 106 antibody CDCA 1 antibody CDCA1 antibody Cell division cycle associated 1 antibody Cell division cycle associated protein 1 antibody Cell division cycle-associated protein 1 antibody CT106 antibody hNuf 2 antibody hNuf2 antibody hNuf2R antibody 展开
Function :
This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2.4-Acetoxystyrene uses Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.5458-56-0 In stock Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.PMID:33599915 The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within Human Nuf2 aa 1-108 / 464.
Species reactivity:
Human
Verify application:
WB, FC
Coupling :
unconjugated
Clone number:
JG34-64
RRID:
AB_3070810
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 54 kDa
Positive control :
K562 cell lysate, PC-3M cell lysate, THP-1 cell lysate, A431.