Product Name :
NIPBL Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
CDLS antibody Colon tumor susceptibility 2 antibody Delangin antibody DKFZp434L1319 antibody FLJ11203 antibody FLJ12597 antibody FLJ13354 antibody FLJ13648 antibody FLJ44854 antibody IDN 3 antibody 展开
Function :
This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Two transcript variants encoding different isoforms have been found for this gene.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthesized peptide derived from human protein . at AA range: 560-640
Species reactivity:
Human, Mouse
Verify application:
IHC-P
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Fmoc-β-azido-Ala-OH site Aliquot store at -20℃ or -80℃.2-(Oxetan-3-yl)acetic acid Purity Avoid repeated freeze / thaw cycles.PMID:33577249
Storage buffer solution:
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
308 kDa
Positive control :
Cerebellum,Endometrium,Epithelium,Testis,Urinary bladder,