Product Name :
NKX3.1 Recombinant Rabbit Monoclonal Antibody [JE36-27]

Predicted band size :
26 kDa

Observed band size :
30 kDa

Synonyms:
BAPX 2 antibody BAPX2 antibody Homeobox protein NK-3 homolog A antibody Homeobox protein Nkx 3.1 antibody Homeobox protein Nkx-3.1 antibody Homeobox protein Nkx3.1 antibody NK homeobox (Drosophila) family 3 A antibody NK homeobox family 3 A antibody NK homeobox, family 3, member A antibody NK3 homeobox 1 antibody 展开

Function :
Homeobox protein Nkx-3.1, also known as NKX3-1, NKX3, BAPX2, NKX3A and NKX3.1 is a protein that in humans is encoded by the NKX3-1 gene located on chromosome 8p. NKX3-1 is a prostatic tumor suppressor gene. NKX3-1 is an androgen-regulated, prostate-specific homeobox gene whose expression is predominantly localized to prostate epithelium. It acts as a transcription factor that has critical function in prostate development and tumor suppression. It is a negative regulator of epithelial cell growth in prostate tissue. The NKX3-1 homeobox protein is encoded by the NKX3-1 gene. The homeodomain-containing transcription factor NKX3A is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3A protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.

Antibody Type:
Recombinant Rabbit monoclonal Antibody

Immunogen :
Recombinant protein within Human NKX3.1 aa 1-234 / 234.

Species reactivity:
Human

Verify application:
WB, IHC-P

Coupling :
unconjugated

Clone number:
JE36-27

RRID:
AB_3072500

Form :
Liquid

Concentration :
1ug/ul

Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃.2,2-Bis(bromomethyl)-1,3-dioxolane structure Avoid repeated freeze / thaw cycles.Hex-5-yn-1-ol Chemscene

Storage buffer solution:
1*TBS (pH7.PMID:33687113 4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Subtype:
IgG

Purification method :
Protein A affinity purified.

ELTSA :

Molecular weight :
Predicted band size: 26 kDa

Positive control :
A549 cell lysate, RWPE-1 cell lysate, human prostate tissue, human prostate carcinoma tissue, human testis tissue.