Rosine “gatekeeper” residue. Replacement on the “gatekeeper” residues M85 and F
Rosine “gatekeeper” residue. Replacement with the “gatekeeper” residues M85 and F95 in APH(2 )-IIa and APH(2 )-IVa, respectively, by tyrosine does not drastically adjust the antibiotic susceptibility profiles produced by…